Scientific Resources

Substrate specificity profiling by phage display highlights previously unknown protease promiscuity

A drug discovery company working on a protease inhibitor faced challenges translating their biochemical results to a cellular setting. Learn how Tango Biosciences utilized an innovative approach to phage display to rapidly screen billions of peptide sequences to profile the protease substrate specificity, revealing novel targets that enabled the company to pivot their discovery project and achieve critical milestones on time.

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