Scientific Resources

Mapping Intracellular Protein Networks | 13 | Phage Display In Biotech

In recent years, it has become well recognized that eukaryotic cells utilize protein-protein interactions for a number ofcellular processes, such as assembly of the cytoskeleton,transference of signals during signal transduction, and to compartmentalize proteins. Protein interaction modules oftenserve to mediate these protein-protein interactions, and have the following properties: they are typically 60-140 aminoacids in length, fold autonomously within the context of the protein that contains the module, and bind short (i.e., 4-7amino acids) segments of other proteins.

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